L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications

L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications

An essential component of the human diet, L-tryptophan is critical in a number of metabolic functions and has been widely used in numerous research and clinical trials. This review provides a brief overview of the role of L-tryptophan in protein synthesis and a number of other metabolic functions. With emphasis on L-tryptophan's role in synthesis of brain serotonin, details are provided on the ...

Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine.

Mitochondria play important roles in human physiological processes, and therefore, their dysfunction can lead to a constellation of metabolic and nonmetabolic abnormalities such as a defect in mitochondrial gene expression, imbalance in fuel and energy homeostasis, impairment in oxidative phosphorylation, enhancement of insulin resistance, and abnormalities in fatty acid metabolism. As a conseq...

Belief Functions in Accounting Behavioral Research

Behavioral accounting research deals with a complex set of phenomenon including the broad domain of human decision making under uncertainty. Two aspects of decision making of particular relevance to accounting and auditing research are two constructs that are inexorably interrelated: uncertainty and information (evidence). This paper introduces a theoretical perspective that enriches the knowle...

Trends in basic, translational, epidemiological and therapeutic research in cancer.

Visceral Pain: Basic Research Concepts and Therapeutic Interventions

The accumulation of nociceptive diseases that limit normal body functions is a major risk factor for a disability, and visceral pain is one of the most prevalent human health problems. Additionally, many pain-associated diseases are accompanied by the concomitant decline in cognitive and motor performance. The complex interplay and balance between diverse signal transduction mediators, genetic ...